Seth Rogen Dale Denton James Franco Saul Silver Gary Cole Ted Danny McBride Red Rosie Perez Carol Kevin Corrigan Budlofsky Craig Robinson Matheson Amber Heard Angie Anderson Ed Begley Jr. Robert Nora Dunn Shannon Bobby Lee Bobby James Remar General Bratt Joe Lo Truglio Mr. Edwards Art Napiontek Clark Cleo King Police Liaison Officer Bill Hader Private Miller Jonathan Spencer Scientist Dana Lee Cheung Ken Jeong Ken Connie Sawyer Faye Belogus David McDivitt Cop with Mole Mae LaBorde Mrs. Mendelson Jeannetta Arnette Sandra Danby Omar Leyva Guy in Car #2 Jack Kehler Walter - Accountant Robert Longstreet Dr. Terrence Peter Gray Lewis Thug #1 - Peter Steve Bannos Thug #2 - Jared Eddie Rouse Thug #5 - Lance Brian Scannell Thug Troy Gentile Troy (uncredited)