Tom Holland Peter Parker / Spider-Man Zendaya Michelle 'MJ' Jones Benedict Cumberbatch Stephen Strange / Doctor Strange Jacob Batalon Ned Leeds Jon Favreau Harold 'Happy' Hogan Jamie Foxx Max Dillon / Electro Willem Dafoe Norman Osborn / Green Goblin Alfred Molina Dr. Otto Octavius / Doctor Octopus Benedict Wong Wong Tony Revolori Eugene 'Flash' Thompson Marisa Tomei May Parker Andrew Garfield Peter Parker / Spider-Man Tobey Maguire Peter Parker / Spider-Man Angourie Rice Betty Brant Arian Moayed Agent Cleary Paula Newsome MIT Assistant Vice Chancellor Hannibal Buress Coach Wilson Martin Starr Mr. Harrington J.B. Smoove Mr. Dell J.K. Simmons J. Jonah Jameson Rhys Ifans Dr. Curt Connors / The Lizard Charlie Cox Matt Murdock Thomas Haden Church Flint Marko / Sandman Rudy Eisenzopf Arena Bystander Ben VanderMey Man in Car Gary Weeks Agent Foster Gregory Konow Donut Shop Boss Anisa Nyell Johnson School Security Guard Regina Ting Chen Reporter Robert Mitchel Owenby Daily Bugle Lackey Glenn Keogh British Reporter Paris Benjamin British Anchor Cristo Fernández Bartender Tom Hardy Eddie Brock / Venom (uncredited)