Steve Martin Tom Baker Eugene Levy Jimmy Murtaugh Bonnie Hunt Kate Baker Tom Welling Charlie Baker Piper Perabo Nora Baker-McNulty Hilary Duff Lorraine Baker Carmen Electra Sarina Murtaugh Jaime King Anne Murtaugh Taylor Lautner Eliot Murtaugh Alyson Stoner Sarah Baker Jonathan Bennett Bud McNulty Jacob Smith Jake Baker Liliana Mumy Jessica Baker Morgan York Kim Baker Kevin G. Schmidt Henry Baker Forrest Landis Mark Baker Brent Kinsman Nigel Baker Shane Kinsman Kyle Baker Blake Woodruff Mike Baker Alexander Conti Kenneth Murtaugh Melanie Tonello Becky Murtaugh Robbie Amell Daniel Murtaugh Shawn Roberts Calvin Murtaugh Peter Keleghan Mike Romanow Damon Runyan Tennis Pro Matthew Knight Theatre Kid Lee MacDougall Doobner Dad Haylee Wanstall Doobner Daughter Ely Henry Doobner Younger Son Tre Smith Security Guard Adam Shankman Clam Bake Chef Shawn Levy Hospital Intern Ben Falcone Theatre Patron Kelly Keaton Theatre Patron