Keanu Reeves Thomas A. Anderson / Neo Carrie-Anne Moss Tiffany / Trinity Yahya Abdul-Mateen II Morpheus / Agent Smith Jessica Henwick Bugs Jonathan Groff Smith Neil Patrick Harris The Analyst Priyanka Chopra Jonas Sati Christina Ricci Gwyn de Vere Jada Pinkett Smith Niobe Telma Hopkins Freya Chad Stahelski Chad Lambert Wilson The Merovingian Brian J. Smith Berg Toby Onwumere Sequoia Max Riemelt Sheperd Eréndira Ibarra Lexy Andrew Lewis Caldwell Jude Michael X. Sommers Skroce Stephen Dunlevy Agent Jones Ellen Hollman Echo William W. Barbour Businessman (uncredited) Kenny Beers SWAT Team Member / Runner (uncredited) Erwin Felicilda Runner (uncredited) Laurence Fishburne Morpheus (uncredited) (archive footage) Hugo Weaving Agent Smith (uncredited) (archive footage)